A ruptured gastrointestinal stromal tumour of the small intestine: a case report

Ivan Lolli, Sergio Diotaiuti, Silvana Russo, Giovanna A. Campanella, Nicola Giampaolo, Gioacchino Leandro, Vincenzo Defilippis

DOI: https://doi.org/10.7175/cmi.v5i1S.1101


The management of Gastrointestinal Stromal Tumours (GISTs) has evolved rapidly since imatinib was introduced. Surgery remains the first-line treatment for localised, primary GIST, but the risk for local or metastatic relapse of disease is very high. Prognostic assessment is a critical part of developing a treatment strategy. Perforation or rupture of a GIST to the abdominal cavity has a very high risk for recurrence. We described the case of a 51-year-old man with a haemoperitoneum caused by a ruptured primary GIST of the small intestine. After complete surgical resection, imatinib given for two years as adjuvant therapy achieved no disease progression after prolonged follow-up.


Ruptured gastrointestinal stromal tumour (GIST); Small intestine; Adjuvant imatinib

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