A complicated case of pulmonary embolism in a patient with renal failure

Fulvio Pomero, Chiara Brignone, Giovanni Gollè, Alberto Silvestri, Elena Migliore, Christian Bracco, Cristina Serraino, Elisabetta Castagna, Sara Severini, Luigi M. Fenoglio

DOI: https://doi.org/10.7175/cmi.v4i3S.1154


We describe a case of pulmonary embolism with instable hemodynamics in a patient with renal failure; the case is complicated by heparin-induced thrombocytopenia (HIT). Renal failure has a high prevalence in hospitalized patients and is a restriction on administration of low molecular weight heparins (LMWH) and fondaparinux. HIT is a potentially life-threatening complication, therefore a precocious diagnosis is essential. Therapy consists in the immediate stop of heparin’s administration and in the administration of non-heparin antithrombotic drugs.


Pulmonary embolism; Renal failure; Heparin-induced thrombocytopenia; Fibrinolysis; Caval filter

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