Vision Impairment After Iron Chelating Agent in a Patient Under Peritoneal Dialysis

Chi-Feng Huang



A 54-year-old female patient had a history of end-stage renal disease (ESRD) under continuous automatic peritoneal dialysis (CAPD) therapy for 6 years. She had underlying hypertension history under oral hypertensives (olmesartan medoxomil). She was admitted to the ward for iron chelating agent therapy due to high ferritin level (5480 ng/ml). Deferoxamine 1 gram was prescribed with intravenous drip for 24 hours for 5 days. On the fifth day, she complained about vision problems, i.e. central halo pattern vision loss. A deferoxamine-related macula edema was diagnosed. After discontinuing the medication, her vision gradually improved. After 3 months of follow up, her vision disorders recovered.

Although we reduced the dose of iron chelating agent, vision side effects also occurred in this ESRD patient.

This case taught us to perform a careful detection of vision problems before, during, and after deferoxamine therapy in order to prevent irreversible vision disorders.


Vision Disorders; Kidney Failure, Chronic; Peritoneal Dialysis (PD); Deferoxamine.

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