Coronavirus Disease 2019 (COVID-19): A Brief Report

Domenico Lorenzo Urso



Severe acute respiratory syndrome (“SARS-CoV-2”, previously provisionally named “2019 novel coronavirus” or “2019-nCoV”) disease (COVID-19) in China, at the end of 2019, resulted in a large global outbreak.

Among patients with pneumonia caused by SARS-CoV-2, fever is the most common symptom, followed by dry cough. Bilateral lung involvement with ground-glass opacities (GGOs) is the most common finding from computed tomography (CT) images of the chest.

At present, there are no specific antiviral drugs against SARS-CoV-2 infection for potential therapy of humans. Current treatments are mainly focused on symptomatic and respiratory support in patients with COVID-19. Preventive measures are the current strategy to limit the spread of cases.

The present report summarizes the point of the situation about this global emergency.


SARS-CoV-2; Coronavirus; Pandemic; Pneumonia; Respiratory Support

Full Text



  • Lu H, Stratton CW, Tang YW, et al. Outbreak of pneumonia of unknown etiology in Wuhan China: the mystery and the miracle. J Med Virol 2020; 92: 401-2;
  • Zhu N, Zhang D, Wang W, et al. A Novel Coronavirus from Patients with Pneumonia in China, 2019. N Engl J Med 2020; 382: 727-33;
  • World Health Organization, WHO Director-General’s Remarks at the Media Briefing on 2019-nCoV on 11 February 2020. (2020). Available at (last accessed April 2020)
  • Gorbalenya AE, Baker SC, Baric RS, et al. The species Severe acute respiratory syndrome-related coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2. Nat Microbiol (2020); 5: 536-44;
  • Delamater PL, Street EJ, Leslie TF, et al. Complexity of the Basic Reproduction Number (R0). Emerg Infect Dis 2019; 25: 1-4;
  • Riou J, Althaus CL. Pattern of early human-to-human transmission of Wuhan 2019 novel coronavirus (2019-nCoV), December 2019 to January 2020. Eurosurveillance 2020; 25: 2000058;
  • World Health Organization, WHO Director-General’s Remarks at the Media Briefing on COVID-19 on 11 March 2020. (2020). Available at (last accessed April 2020)
  • World Health Organization, Coronavirus Disease 2019 (COVID-19) Situation Report 71. (2020). Available at (last accessed April 2020)
  • Novel Coronavirus Pneumonia Emergency Response Epidemiology Team. Vital surveillances: the epidemiological characteristics of an outbreak of 2019 novel coronavirus diseases (COVID-19) - China, 2020. China CDCWeekly. Available at (last accessed April 2020)
  • Wu Z, McGoogan JM. Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China: Summary of a Report of 72 314 Cases From the Chinese Center for Disease Control and Prevention. JAMA Published online February 24, 2020;
  • Global Surveillance for human infection with coronavirus disease (COVID-19) Interim guidance 27 February 2020 (2020). Available at (last accessed April 2020)
  • Li Q, Med M, Guan X, et al. Early transmission dynamics in Wuhan, China, of novel coronavirus-infected pneumonia. N Engl J Med 2020; 382: 1199-207;
  • Huang C, Wang Y, Li X, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet 2020; 395: 497-506;
  • Zhu N, Zhang D, Wang W, et al. A novel coronavirus from patients with pneumonia in China, 2019. N Engl J Med 2020; 382: 727-33;
  • Chen N, Zhou M, Dong X, et al. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study. Lancet 2020; 395: 507-13;
  • Jiang F, Deng L, Zhang L, et al. Review of the Clinical Characteristics of Coronavirus Disease 2019 (COVID-19). J Gen Intern Med (2020); Published 4 March 2020;
  • Clinical management of severe acute respiratory infection (SARI) when COVID-19 disease is suspected. Interim guidance 13 March 2020 (2020). Available at (last accessed April 2020)
  • Lippi G, Plebani M. Laboratory abnormalities in patients with COVID-2019 infection, Clinical Chemistry and Laboratory Medicine (CCLM) (published online ahead of print 3 March 2020), 20200198;
  • Han R, Huang L, Jiang H, et al. Early Clinical and CT Manifestations of Coronavirus Disease 2019 (COVID-19) Pneumonia. AJR Am J Roentgenol 2020: 1-6;
  • Peng QY, Wang XT, Zhang LN; Chinese Critical Care Ultrasound Study Group (CCUSG). Findings of lung ultrasonography of novel corona virus pneumonia during the 2019-2020 epidemic. Intensive Care Med Published 12 March 2020;
  • World Health Organization. (2020). Laboratory testing for coronavirus disease 2019 (COVID-19) in suspected human cases: interim guidance, 2 March 2020. World Health Organization 2020. Available at (last accessed April 2020)
  • World Health Organization. (2020). Infection prevention and control during healthcare when COVID-19 is suspected. Available at (last accessed April 2020)


Abstract: 2710 views
HTML: 751 views
PDF: 535 views


  • There are currently no refbacks.