Atypical presentation of Non-Hodgkin Lymphoma (NHL): a case report

Fabiola Mastropietro, Alessandra Piccini, Giulia Lucignani, Alfonso Rubino, Giancarlo Fiermonte

DOI: https://doi.org/10.7175/cmi.v8i4.942

Abstract

Lymphomas infrequently cause peripheral nerve complications. These syndromes mostly occur by direct compression or infiltration of nerves (neurolymphomatosis), but may also be due to a remote effect as paraneoplastic syndromes, neurotoxic complications of chemotherapy, antibody-mediated or autoimmune mechanisms.

We report the case of a 60-year-old woman who presented with a complex peripheral nervous system involvement as initial manifestation of Non-Hodgkin Lymphoma (NHL). This case sheds light on “protean” mechanism of peripheral nerve complications during the course of NHL and related diagnostic dilemma.

Keywords

Neurolymphomatosis; Paraneoplastic syndrome; Non-Hodgkin Lymphoma

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