Risk factors for young ischemic stroke and the enigma of trombophilic polymorphisms: a case report

Linda Iurato, Marialuisa Ventruto, Maria Adalgisa Police, Alessandro Morella, Alfonso Fortunato, Lanfranco Musto, Patrizia Fiori, Mario Nicola Vittorio Ferrante, Antonio Monaco

DOI: https://doi.org/10.7175/cmi.v5i4.497


We report the case of a 48-year-old female patient with stroke family history that was admitted in our ward with suspected ischemic stroke diagnosis. The diagnostic process is described in detail, paying attention in particular to anamnestic data and to genetic polymorphisms related to higher risk for inherited thrombophilia. At the end, the diagnosis indicates red infarct in a migraine patient with cerebrovascular and cardiovascular risk factors of undetermined aetiology according to TOAST criteria. Some of the known thrombophilic polymorphisms were found in the patient: however not all the mentioned thrombophilic markers are universally recognized as predisposing factors for arterial ischemic stroke.


Young stroke; Thrombophilia; Ischemic risk factors

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