Unexpected spontaneous remission of HCV in a patient with chronic HIV infection

Roberto Manfredi

DOI: https://doi.org/10.7175/cmi.v4i1.537


We report an exceptional case of resolution of HCV infection in a HIV-infected patient. The patient, a 49-year-old male with history of drugs addiction, suffered from an evolutive liver disease never treated with specific anti-HCV compounds during two decades. The case report highlights a rare phenomenon, seldom reported in medical literature (a PubMed search retrieved only 8 similar cases), and underlines the importance of a deeper investigation of all the virologic, immunological, pathogenetic, and therapeutic implications.


HIV-HCV co-infection; Spontaneous clearance of HCV virus; HAART; Compliance

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